Why must samples be correctly positioned during coagulation testing?

Correct positioning of samples during coagulation testing is essential to ensure accurate results in clotting time. When samples are not positioned correctly, factors such as gravitational effects, bubble formation, or improper mixing can lead to variations in the blood sample's behavior. Coagulation tests measure how well and quickly blood clots, and even slight discrepancies in sample handling can alter the test outcomes, leading to false positives or negatives.

Proper positioning helps maintain the integrity of the blood sample, ensuring that any activated clotting factors or inhibitors are accurately represented. This positioning also ensures that the sample is consistently tested under controlled conditions, reflecting the true physiological state of the client's coagulation profile. Overall, precision in sample handling is fundamental to reliable and reproducible laboratory results.